one step forward and two (painful) steps back

As y'all know, managing RA can be so difficult!!  I recently stopped taking methotrexate because (according to my rheumatologist)  research suggests that it may cause rheumatoid nodules and I have a very big nodule on the bottom of my foot that is painful.  When I first stopped taking the medication I felt bettter and my foot hurt less....today, it was excruciating!!  So hard to know what the best thing to do is.  Luckily, I feel like I have a good team to help me make a decision. Gotta look on the bright side, right?

What makes you the most frustrated about this crazy disease?